Research news · Nature

P450 enzyme forges rare Tyr–Trp cross-link in peptide

P450 enzyme forges rare Tyr–Trp cross-link in peptide

Nature reported in September 2026 that P450 cyptide synthase KwwB catalyzes a non-native cross-link at Tyr-C3–Trp-N1 and tolerates leader peptide mutations.

Source: P450 cyptide synthase KwwB catalyzes non-native cross-link at Tyr-C3–Trp-N1 and tolerates leader peptide mutations (Nature)

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