6 compounds
Metabolic
Energy, appetite and metabolic-signalling research
AOD-9604
Studied in fat-cell lipid-metabolism models.
Cagrilintide
Studied at the amylin receptor in signalling and energy-homeostasis models.
MOTS-c
Studied in AMPK signalling and how cells keep their energy in balance.
Retatrutide
Studied at three gut-hormone receptors at once: GIP, GLP-1 and glucagon.
Semaglutide
Studied in gut-hormone (GLP-1) receptor signalling models.
Tirzepatide
Studied in gut-hormone (GIP and GLP-1) receptor signalling models.
Metabolic research
All articlesWhat the published literature on these compounds actually examined — the model, the endpoint, and the result.
Metabolic
Amylin, a growth-hormone fragment, and two different evidence levels
Cagrilintide has a published human trial. AOD-9604 has mouse work and a clinical programme that failed. Both sit in the same part of the catalog.
Metabolic
Incretin receptors: one, two, or three
GLP-1, GIP and glucagon receptors, and what the single-, double- and triple-agonist trials set out to measure.