Research news · Nature

One handle does two jobs in macrocyclic peptide synthesis

October 14, 2026

Nature reported in October 2026 that chemists developed a general synthesis of tryptophan-crosslinked macrocyclic peptides enabled by a dual-functional directing group.

Source: A general synthesis of tryptophan-crosslinked macrocyclic peptides enabled by a dual-functional directing group (Nature)

Related in the Skinni library

Handling lyophilised peptides at the bench

For research use only. This brief summarises a third-party report; it is not a claim about any Skinni product and not medical advice.

More research news

All briefs

Research news · Manufacturing Chemist

Peptide Quality Standards Shift as Development Advances

Manufacturing Chemist reported in October 2026 that peptide quality requirements change as a compound moves from research grade through to GMP, with distinct standards applying at each stage of development.

October 22, 2026Read the brief

Research news · Big Easy Magazine

Potency data that cannot travel between labs

Big Easy Magazine reported in October 2026 that assay reproducibility for melanocortin peptides is under scrutiny, with potency data shown not to transfer reliably between laboratories.

October 21, 2026Read the brief

Research news · Bioengineer.org

Peptide Edits Produce Unpredictable Anti-Inflammatory Results

Bioengineer.org reported in October 2026 that FELL peptide edits reveal unpredictable anti-inflammatory activity, according to new research findings.

October 20, 2026Read the brief