
About this compound
MOTS-c is a 16-residue peptide encoded not in the nuclear genome but in mitochondrial DNA - specifically within the 12S rRNA region. It belongs to the small class of mitochondrial-derived peptides identified since 2015.
Studied in
- AMPK signalling
- Mitochondrial research
- Metabolic homeostasis
Compound identity
| Compound | MOTS-c |
|---|---|
| CAS number | 1627580-64-6 |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2,174.6 Da |
Specifications
- Purity method: HPLC
- Appearance: Lyophilized powder
- Solubility: Reconstitute per protocol; see Supplies for diluents.
- We don't publish a purity percentage here — that figure is only meaningful tied to the lot you actually receive, so it lives on the lot certificate.
Metabolic
MOTS-c
A peptide coded by mitochondrial DNA.
What the research targets
Studied in AMPK signalling and how cells keep their energy in balance.
Research use only
Supplied to qualified professionals and institutions for laboratory research. Not a drug, supplement or cosmetic, and not for human or veterinary use. We publish no dosing or administration guidance of any kind.
Supply formats
Buy one, or a case of ten.
Single unit
One unit.
10 mgVial
PS-6963679-10-MG
On verified account
Case — 10-pack
10 of the same size, at the 10-pack price.
Case · 10 × 10 mg
10-pack price — 10 × one unit, per vial.
PS-6963679-C10-10-MG
On verified account
One-time verification of professional or institutional affiliation. No payment is taken on this site.
From the research library
All articlesCited summaries of the published work behind MOTS-c — what was studied, in which model, and what was measured.
Metabolic
Amylin, a growth-hormone fragment, and two different evidence levels
Cagrilintide has a published human trial. AOD-9604 has mouse work and a clinical programme that failed. Both sit in the same part of the catalog.
Cellular
Mitochondrial peptides, cardiolipin and the NAD+ pool
Mitochondria carry their own DNA and code signalling peptides of their own. A separate class of compounds targets the inner membrane directly.